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This chapter provides an overview of the status of applied econometric research in hospitality and tourism management and outlines the econometric toolsets available for quantitative researchers using empirical data from the field. Basic econometric models, cross-sectional models, time-series models, and panel data models are reviewed first, followed by an evaluation of relevant applications. Next, econometric modeling topics that are germane to hospitality and tourism research are discussed, including endogeneity, multi-equation modeling, causal inference modeling, and spatial econometrics. Furthermore, major feasibility issues for applied researchers are examined based on the literature. Lastly, recommendations are offered to promote applied econometric research in hospitality and tourism management.